Monday, Lunes
October 10
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LOCATION: LA PAZ AT THE HIGH ALTITUDE PULMONARY AND
PATHOLOGY INSTITUTE
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08:00-08:30
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Newcomer Registration. Registro de nuevos participantes
IPPA Building
(1st Floor) Edificio IPPA (Multicolor) Av. Copacabana Prolongacion # 55,
Estacion Avenida del Poeta Telefericos Celeste y Blanco
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Chairman: Prof. Dr. Gustavo Zubieta-Calleja
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08:30-08:35
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Opening Words by
Prof. Thuppil Venkatesh. M.D.
President of the International Society of Chronic Hypoxia
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INDIA
18:30
Virtual
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08:35-08:40
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UNESCO/UNITWIN Department of
Environmental Health
Prof. Kusal Das
BLDE University, Vijayapur, India
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INDIA
18:35
Virtual
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08:40-08:50
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The Life of Dr. Carlos
Monge Medrano and Dr. Alberto Hurtado
Dr. Roberto Accinelli
Tanaka
Instituto de Investigaciones de la Altura
Universidad Cayetano Heredia, Lima, Peru
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La Paz
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08:50-09:20
KEYNOTE
SPEAKER
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Chronic
Hypoxia: a remarkable stimulus for enhanced survival
Prof. Dr. Gustavo Zubieta-Calleja
High Altitude Pulmonary and Pathology Institute,
Instituto Pulmonar y Patologia
en la Altura
(HAPPI-IPPA) 52nd Anniversary, La Paz, Bolivia
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La Paz
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EXERCISE & BREATHING AT HIGH ALTITUDE
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09:20-09:50
KEYNOTE
SPEAKER
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Factors
affecting the exercise performance of highland natives in the Andes and
Himalayas
Prof. Tom Brutsaert,
PhD
Exercise Physiology
Anthropology Dept
Falk College
Syracuse University
New York, Washington D.C., USA
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La Paz
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09:50-10:20
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Beneficial
effects of “PRANAYAMA” (regulated breathing) at high altitude hypoxic
conditions – a new thought
Prof. Thuppil
Venkatesh, M.D.
The Lead Man of India
Foundation for Quality India
President of the International Society of Chronic Hypoxia
Bangalore, India
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INDIA
19:45
Virtual
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10:20-10:40
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******* Break, Refrigerio
*******
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COVID-19 AT HIGH ALTITUDE
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Chairman: Dr. Natalia Zubieta-DeUrioste, M.D.
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10:40-11:00
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Biophysical
effects of high altitude on the susceptibility of the living cells to corona
virus infection
Prof. Hamid Mobasheri PhD
Head of Laboratory of Membrane Biophysics and Macromolecules Institute of Biochemistry and Biophysics
University of Tehran
Coordinator of UNESCO/UNITWIN Network in Biophysics Biotechnology and Environmental Health
Tehran, Iran
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IRAN
18:30
Virtual
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11:00-11:20
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Hypoxia,
normoxia and hyperoxia: what have we learned from critically ill patients?
Prof. Paolo Pelosi, M.D.
Chief Professor in Anaesthesia and Intensive Care,
Head of Anaesthesia and Intensive Care Unit at IRCCS San Martino-IST Head of
the Anaesthesia and Intensive Care Unit
Genoa, Italy
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ITALY
17:20
Virtual
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11:20-11:40
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Lower Case Fatality Rate of COVID-19 in
cities above 2,500m in Bolivia, Ecuador, Colombia, Peru and Mexico
Dra. Natalia Zubieta-DeUrioste,
M.D.
High Altitude Pulmonary and Pathology Institute (HAPPI-IPPA)
La Paz, Bolivia
PHD student
University of Calgary,
Calgary, Canada
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La Paz
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11:40-12:00
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Obesity
and Hypobaric Hypoxia, allies in survival of COVID-19
Prof. Jorge Luis Velez M.D. MSc. PhD
Head of Department Critical Medicine
Central University of Ecuador
Pablo Arturo Suarez Hospital
Quito, Ecuador
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La Paz
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12:00-12:20
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Elevated
Humoral Immune Response to SARS-CoV-2 at High Altitudes Revealed by an
Anti-RBD ′In-House′ ELISA
Dr. Rodrigo Hernan Tomas Grau, PhD
Postdoctoral fellow
Post-Doc
IMMCA
Instituto de Investigación en Medicina Celular y Molecular Aplicada
(CONICET-UNT-SIPROSA). Tucuman, Argentina
Tucuman, Argentina
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Tucuman 13:00-13:20
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12:20-12:40
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Low
Serum Erythropoietin Levels are Associated with Fatal COVID-19 Cases at 4,150
meters above sea level
Dr. Antonio Viruez, MD
Master in Bioethics
Head of the Critical Care Department, Hospital del Norte, El Alto-La Paz,
Bolivia
President of the Scientific Committee of the Bolivian Society of Critical
Medicine and Intensive Care, Filial La Paz
Director of the Department of Critical Medicine of the Latin American
Thoracic Association
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La Paz
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12:40-13:20
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Lunch Break. Almuerzo libre
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13:30
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Shuttle departure from IPPA to Comando de la Armada. for the next conference presentations. Traslado al Comando de la Armada en Seguencoma para continuar la conferencia
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LUNG & RESPIRATORY CONTROL AT HIGH
ALTITUDE
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Chairman: Prof. Dr. Gustavo Zubieta-Calleja
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14:30-14:50
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The
′safety factors′ protecting against the development of lung
edema; a functional interpretation of pulmonary hypertension
Prof. Giuseppe Miserocchi,
MD
Former Prof. of Physiology and Biophysics
Università degli Studi di Milano – Bicocca
Italia
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ITALY
20:30
Virtual
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14:50-15:10
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High
Altitude Pulmonary Edema in Children: A systematic Review
Dr. Jose A. Castro-Rodriguez, MD. PhD. ATSF
Full Professor
Pediatric Pulmonologist
School of Medicine
Pontificia Universidad Católica de Chile
Santiago, Chile
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La Paz
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15:10-15:30
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Endothelial
function at high altitude
Prof. Walter Calderon Gerstein M.D.
Universidad Continental de Ciencias e Ingenieria
Huancayo, Peru
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La Paz
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15:30-15:50
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Oxygen
saturation parameters and apnea/hypopnea index in children at high altitude
Prof. Santiago Ucros
M.D. PhD
Department of Pediatrics,
Pediatric Respiratory Medicine.
Fundacion Santa Fe de Bogota
Bogota, Colombia
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La Paz
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15:50-16:10
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Asthma
at high altitude
Dr. Roberto Accinelli
Tanaka, M.D.
Former Director Instituto
de Investigaciones de la Altura,
University Cayetano Heredia,
Lima, Peru
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La Paz
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16:10-16:40
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Chronic
Hypoxia: The optimal environment for space travel and human settlements in space
Prof. Dr. Gustavo Zubieta-Calleja
High Altitude Pulmonary and Pathology Institute,
Instituto Pulmonar y Patologia
en la Altura
(HAPPI-IPPA) 52nd Anniversary, La Paz, Bolivia
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La Paz
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18:00-19:00
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INAUGURATION
CEREMONY
Auditorium of Comando de la Armada (Bolivian Navy)
Seguencoma
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La Paz
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19:00-21:00
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Formal Opening Dinner at the "Armada Flag Saloon" 8th floor
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Tuesday, Martes October 11
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TIWANACU (3800m)
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08:00
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Trip to Tiwanaku from IPPA (Teleferico Celeste) ruins,
Visit the Museum. Viaje
a Tiwanaku Paseo turístico Museo Arqueológico.
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12:30
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Trip to Guaqui, Lake Titicaca - viaje a
Guaqui
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13:00-14:00
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Lunch - Almuerzo
en el Barco Multipropósito de la Armada Boliviana
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METABOLIC
CHANGES AT HIGH ALTITUDE
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Chairman: Prof. Tom Brutsaert, PhD
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14:00-14:20
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Sympathovagal imbalance drives the chronic sustained
hypoxia induced impairment of glucose homeostasis in normobaric
experimental rats. Role of L/N type calcium channel blocker (cilnidipine)
Prof. Shrilaxmi Bagali, PhD
Professor
Laboratory of Vascular Physiology and Medicine
Department of Physiology
Shri B.M.Patil Medical College
BLDE (Deemed to be University)
Vijayapur-586103, Karnataka, INDIA
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INDIA
23:30
Virtual
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14:20-14:40
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Chronic
hypoxia triggers mitochondrial plasticity in the brain of mice, but not in
rats
Christian Arias Reyes , PhD. (c)
Faculty of Medicine. CR
IUCPQ/ Universite Laval.
Quebec, Canada
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La Paz
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14:40-15:00
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Postnatal
hypoxia alters mitochondrial oxygen consumption and affinity in mice, but not
in rats.
Maud Demarest
Ph.D.
candidate
Université Laval
Québec, Canada
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La Paz
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15:00-15:30
KEYNOTE
SPEAKER
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Metabolic
responses to intermittent hypoxia are modulated by sex hormones in male and
female mice
Prof. Vincent Joseph, PhD
Professor of Physiology Laval University
Departement de Pediatrie,
Universite Laval
Quebec, Canada
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La Paz
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15:30-15:50
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******* Break, Refrigerio *******
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POSTERS SESSION
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Chairman: Lic. Karen Losantos Ramos
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15:50-16:00
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Technical
adjustments for reliable assessment of mitochondrial COX complex activity
in liver samples of rats exposed to chronic hypoxia.
Adriana
Torrico-Cardoso
Universidad Mayor de San AndrésLa
Paz, Bolivia
Institute Universitaire
de Cardiologie et de Pnéumologie
de Québec.
Université Laval
Québec, Canada
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CANADA
15:50
Virtual
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16:00-16:10
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A
nanocurcumin and pyrroloquinoline quinone formulation averts soleus muscle
atrophy under hypobaric hypoxia
Asha Devi Kushwaha
Defence
Institute of Physiology and Allied Sciences
Timarpur, India
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INDIA
01:30 (+ 1 day)
Virtual
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16:10-16:20
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MicroRNA
is associated with cardiac dysfunction in diabetes mellitus
Anna Zhukovska
Bogomoletz Institute of
Physiology
Kyiv, Ukraine
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UKRAINE 23:10
Virtual
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16:20-16:30
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Trombosis venosa cerebral con transformación
hemorrágica a los 6050 msnm en el cerro Aconcagua - Mal agudo de montaña
Andrea
Verónica Marengo
Hospital Alfredo Perrupato.
Argentina
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La Paz
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16:30-16:40
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Escaladores sanos con lesión axonal periférica
por altitud determinada por estudios de neuroconducción
Andrea
Verónica Marengo
Hospital Alfredo Perrupato.
Argentina
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La Paz
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16:40-16:50
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Mitochondrial
responses to HIF-1 and acute hypoxia might underlie adaptation to high altitude
in mice.
Maud Demarest
Ph.D.
candidate
Université Laval
Québec, Canada
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La
Paz
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16:50
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Return to the city
of La Paz Retorno a la ciudad de La Paz
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18:00-19:00
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Free
evening
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Wednesday, Miércoles October
12
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TITICACA LAKE (3800m)
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08:00
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Trip to
TITICACA LAKE Salida al LAGO TITICACA from IPPA (Teleferico Blanco)
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11:15
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Arrival Llegada
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11:15-12:30
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Tour
through the Lake and Visit to the High Altitude Diving Training Center, Tiquina
Visita al Centro de Instruccion
de Buceo en Altura (CIBA)
en Tiquina
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11:15-11:30
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Efectos de la medicina hiperbarica en pacientes con anemia moderada a severa como terapia alternativa de tratamiento a 3810 metros sobre el nivel de mar
Dr. Favio Muñoz, M.D.
Medico
Centro de Instrucción de Buceo de Altura
Armada Boliviana
Titicaca Lake
Tiquina, Bolivia
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Tiquina
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13:00-14:00
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Lunch - Almuerzo
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CELL AND
MOLECULAR MECHANISMS IN HYPOXIA AND CANCER
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Chairman: Christian Arias Reyes, PhD. (c)
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14:00-14:30
KEYNOTE
SPEAKER
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HIF-2 and the carotid body
Dr. Tammie Bishop, Ph.D.
University Research Lecturer
Hypoxia and Cancer
Nuffield Department of Medicine
Comparative & Evolutionary Physiology
University of Oxford
Oxford, England
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ENGLAND
19:00
Virtual
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14:30-14:50
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The
dysfunction of Na/K pump driving water efflux from the cells as a primary
mechanism for cell pathology
Prof. Sinerik Ayrapetyan, PhD
Chair at Life Sciences International Postgraduate Educational Center
UNESCO Chair in Life Sciences
UNESCO/UNITWIN Interregional NETWORK in Biophysics, Biotechnology and
Environmental Health Yerevan, Armenia
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ARMENIA
22:30
Virtual
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14:50-15:10
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HIF-1 mediated activation of antimicrobial peptide LL-37 in type 2 diabetic patients
Dr. Silvia Zambrana, PhD
Biologist
Instituto de Investigaciones Fármaco Bioquímicas, Universidad Mayor de San
Andrés
La Paz, Bolivia
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La Paz
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15:10-15:30
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Erythropoietin receptor regulates tumor mitochondrial biogenesis through iNOS and pAKT
Dr. Markus Thiersch, PhD
Institute of Veterinary Physiology, Vetsuisse-Faculty
University of Zurich
Zurich, Switzerland
Center for Neuroscience Zurich (ZNZ)
Zurich, Switzerland
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SWITZERLAND
21:10
Virtual
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15:30-15:50
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******* Break, Refrigerio *******
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CHRONIC MOUNTAIN SICKNESS
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Chairman: Dr. Jorge Soliz, PhD
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15:50-16:20
KEYNOTE
SPEAKER
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What has erythropoietin to do with chronic mountain sickness?
Dr. Jorge Soliz, PhD
Full Professor,
CR IUCPQ/ Universite Laval.
Dpt Pediatrie,
Quebec, Canada
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La Paz
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16:20-16:40
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Pulmonary
arterial pressure at rest and during exercise in chronic mountain sickness
Dr. Rodrigo Soria Maldonado
Department of Cardiology and Clinical Research,
Inselspital,
University of Bern, Switzerland
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SWITZERLAND
22:20
Virtual
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16:40-17:00
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Sleep-disordered
breathing and vascular function in Chronic Mountain Sickness
Dr. Théo Meister
Department of Cardiology and Clinical Research,
Inselspital,
University of Bern, Switzerland
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SWITZERLAND
22:40
Virtual
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17:00-17:20
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Should Chronic Mountain Sickness patients (poly-erythrocythemia) be phlebotomized? Se debe sangrar a los poliglobulicos?
Prof. Dr. Gustavo Zubieta-Calleja
High Altitude Pulmonary and Pathology Institute,
Instituto Pulmonar y Patologia
en la Altura
(HAPPI-IPPA) 52nd Anniversary,
La Paz, Bolivia
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La Paz
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17:50
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Return to the city of
La Paz. Retorno
a la ciudad de La Paz.
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Thursday, Jueves
October 13
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LA
PAZ at IPPA (3500 m)
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THE BRAIN AT HIGH ALTITUDE
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Chairman: Dra. Edith M. Schneider Gasseer, PhD.
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09:00-09:30
KEYNOTE
SPEAKER
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Introducing
the brain erythropoietin circle to explain adaptive brain hardware upgrade
and improved performance
Prof. Hannelore Ehrenreich, MD, DVM
Professor of Neurology and Psychiatry
Prof. Hon. of Biology & Psychology
University of Göttingen
Clinical Neuroscience
Max Planck Institute for Multidisciplinary Sciences
Göttingen, Germany
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GERMANY
15:00
Virtual
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09:30-09:50
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Hypoxia
possible frontier for treatment for Motor Neuron Disease (MND)
Vasanth Rao
President Founder Trustee
Motor-Neuron Disease Trust
Dr. Shyama Narang Foundation
Bangalore, India<
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INDIA
19:00
Virtual
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09:50-10:10
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Searching
for the invasive and non-invasive cerebral oxygenation threshold in acute
brain injuries at altitude
Dr. Jose Antonio Carmona M.D.
Universidad Nacional Autónoma de México
México City, México
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La Paz
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10:10-10:30
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Sexual
dimorphism in the brain metabolism at high altitude
Dra. Edith M. Schneider Gasseer, PhD.
Institute of Veterinary Physiology, Vetsuisse-Faculty
University of Zurich
Zurich, Switzerland
Center for Neuroscience Zurich (ZNZ)
Zurich, Switzerland
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La Paz
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10:30-10:50
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******* Break, Refrigerio *******
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10:50-11:20
KEYNOTE
SPEAKER
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Neuroprotective
effect of Mucuna Pruriens derived β-Sitosterol preconditioning on
cerebral ischemic rats
Prof. Kusal K Das PhD FRSB(UK)
Laboratory of Vascular Physiology and Medicine
Department of Physiology
Shri B.M.Patil Medical College
BLDE (Deemed to be University)
Vijayapur-586103, Karnataka, INDIA
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INDIA
20:20
Virtual
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11:20-11:40
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HDAC
inhibition Prevent Hypobaric Hypoxia Induced Neurodegeneration and Memory
Impairment
Shashi Bala Singh
Director
National Institute of Pharmaceutical Education and Research (NIPER) Hyderabad
Was Distinguished Scientist and Director General (Life Sciences) at DRDO HQs
Fellow of National Academy of Medical Sciences (FNASc)
and Indian Academy of Neurosciences (FIAN)
New Delhi, India
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INDIA
20:50
Virtual
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11:40-12:10
KEYNOTE
SPEAKER
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The
role of intermittent and chronic hypoxia in the neuronal control of breathing
and swallowing in health and disease
Prof. Jan Marino Ramirez, PhD
Director of the Center for Integrative Brain Research
Head Laboratory of Vascular Physiology & Medicine
Seattle Children's Hospital
University of Washington
Seattle, USA
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USA
08:40
Virtual
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12:10-12:30
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Update and stablishment of new projects
on the
INTERNATIONAL SOCIETY OF CHRONIC HYPOXIA
Thuppil Venkatesh
President ISCH
Bangalore, INDIA
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INDIA
21:30 (+ 1 day)
Virtual
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12:10-14:00
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Lunch Break. Almuerzo libre
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THE HEART AT HIGH ALTITUDE
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Chairman: Prof. Walter Calderon Gerstein M.D.
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14:00-14:30
KEYNOTE
SPEAKER
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Regulation
of blood volume at high altitude
Dr. Carsten Lundby,
Ph.D.
University of Lillehammer
founder at Detalo Health ApS
Lillehammer, Norway
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NORWAY
20:00
Virtual
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14:30-15:00
KEYNOTE
SPEAKER
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Molecular
Mechanisms of Hypoxia induced Collateralization in the Heart: Lessons from a
porcine model
Prof. Hari S. Sharma PhD, DSc, FIABS, FIEIC
Pathology & Clinical Bioinformatics
Erasmus University,
Rotterdam, Netherlands
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NETHERLANDS
20:30
Virtual
|
15:00-15:20
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Effect
of chronic hypoxia on epitranscriptomic machinery
in the heart
Prof. Marketa Hlavackova;
PhD
Laboratory of Developmental Cardiology
Institute of Physiology of the Czech Academy of Sciences
Prague, Czech Republic
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CZECHIA
21:00
Virtual
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15:20-15:40
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Vitamin
D influences cardiovascular diseases: Role of VEGF
Prof. Lata Mullur, PhD
Professor
Laboratory of Vascular Physiology and Medicine
Department of Physiology
Shri B.M.Patil Medical College
BLDE (Deemed to be University)
Vijayapur-586103, Karnataka, INDIA
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INDIA
00:40 (+ 1day)
Virtual
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15:40-16:00
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******* Break, Refrigerio *******
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PRESENTATIONS IN SPANISH
(simultaneous translation to English)
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Chairman: Dr. Roberto Achinelli Tanaka, M.D.
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16:00-16:20
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Hypertension
and myocardial infarction at high altitude, what is the truth??
Dr. Victor
Felix Loza Chacón, MD
Cardiologist
Hospital de Clínicas Universitario de La Paz
Professor of Cardiology
Universidad Mayor de San Andrés
Founder and President of the Asociación Boliviana de
Aterosclerosis
La Paz, Bolivia
|
La Paz
|
16:20-16:40
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COVID-19
intra-cellular replication; histopathological and immune alterations at
2,500m
Prof. Felipe de Jesús Montelongo, MD
Head of the Intensive Care
Unit
Hospital Las Américas de Ecatepec
Ecatepec, Mexico
|
La Paz
|
16:40-17:00
|
Comparison
of the real pneumatic performance offered by high-flow oxygen therapy and
non-invasive ventilation devices: a bench study
Dr. Aurio Fajardo Campoverdi,
M.D. MSc. MEC. PhD(c)
Head of Respiratory Care
Unit,
Head of Respiratory Care Team,
Hospital de Quilpué,
CEO of WeVent (International Mechanical Ventilation
group)
Member of the Expert Committee of Mechanical Ventilation (FEPIMCTI)
Member of the American Association for Respiratory Care (AARC)
Vina Del Mar, Chile
|
La Paz
|
17:00-17:20
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Management
of acid-base status in the obstetric patient at high altitude
Dr. Antonio Viruez
Terapia Intensiva Obstétrica - Hospital del Norte El Alto, Bolivia
|
La Paz
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17:20-17:35
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Pulmonary hypertension at high altitude
Dr. Carlo Vercosa
Pneumologist . . - Hospital del Torax. La Paz, Bolivia
|
La Paz
|
17:35-17:50
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Higher levels of cytoquines in COVID-19 patients at high altitude as compared to sea level.
Dr. Alfredo Merino
Médico Cirujano . .
Residente de 1er año de Cuidados Intensivos
Miembro del Grupo de Investigación de Medicina Intensiva en Altura ( GIMIA)
Bombero Voluntario de la Compañía de Bomberos La Molina 96
Divemaster de Buceo PADI
|
La Paz
|
17:50-18:00
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COVID-19 en Potosi a 4000 metros sobre el nivel mar
Dr. Jose Manuel Calle
Médico neumólogo . .
Universidad Tomas Frias
Miembro del Grupo de Investigación de Medicina Intensiva en Altura ( GIMIA)
Hospital Daniel Bracamonte
Potosi, Bolivia
|
La Paz
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Friday, Viernes
October 14
|
LA
PAZ at IPPA (3500 m)
|
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ADAPTATION AND ACCLIMATIZATION TO HIGH ALTITUDE
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Chairman: Prof. Vincent Joseph, PhD
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09:00-09:30
KEYNOTE
SPEAKER
|
Respiratory
adaptations to high altitude and their genetic basis in deer mice
Dr. Graham Scott, PhD
Associate Professor
Canada Research Chair
Department of Biology
Comparative & Evolutionary Physiology
McMaster University
Hamilton, Ontario, Canada
|
CANADA
09:00
Virtual
|
09:30-09:50
|
The
life of Alpaca shepherds above 4,800 m in Apolobamba,
Bolivia in the Andean Mountain Range within the climate change context
Dr. Máximo Liberman,
Ph.D.
Biólogo
Full Professor
Instituto de Ecología, Facultad de Ciencias Puras y Naturales
Universidad Mayor de San Andres,
La Paz Bolivia
|
La Paz
|
09:50-10:10
|
Andean
rodents: evolution and high elevation adaptations
Dr. Jorge Salazar Bravo, PhD
Associate Professor, Biological Sciences and
Director, International Center for Arid and Semi-Arid Lands Studies
Texas Tech University
Lubbock, TX 79409
|
La Paz
|
10:10-10:30
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Hepatic
mitochondrial metabolism is higher and develops earlier in high-altitude mice
than in rats
Fernanda Aliaga-Raduán
Ph.D.
student
Université Laval
Québec, Canada
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La Paz
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10:30-10:50
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******* Break, Refrigerio *******
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10:50-11:10
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Relationship
of geographic altitude with Foveal Avascular zone Metrics and Vascular
Density Assessed by OCT Angiography
Dr. Vania Garcia, MD
Ophtalmologist Surgeon
Sub especialist in Retina and images Director
Centro Oftalmologico Vision21
Universidad de Chile
Universidad Mayor de San Andr�s
La Paz, Bolivia
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La Paz
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11:10-11:30
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The
Norwegian Mountain Medical Society and Acid-Base at extreme altitudes
Prof. Johan Kofstad,
M.D. PhD
former Chief Department of Medical Biochemistry Rigshospitalet
Chairman of the Norwegian Mountain Medical Society
Oslo, Norway
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NORWAY
17:10
Virtual
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11:30-11:50
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Dynamics of the functional respiratory system parameters under the influence of mountain meteofactors. Research at the Elbrus Medical-Biological Station
Dr. Natalia I. Aralova,
DSc (Engineering)
Senior Researcher Optimization of Controlled Processes,
Glushkov Institute of Cybernetics of National
Academy of Sciences of Ukraine,
Kiev, Ukraine
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UKRAINE
18:30
Virtual
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19:30-22:00
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Closing
Dinner
Closing words: Palabras de Clausura
Prof. Dr. Gustavo Zubieta-Calleja (Jr)
"Science, Honor and Truth" Award
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