8th CHRONIC HYPOXIA SYMPOSIUM
Oct 10 - 15, 2022 La Paz - Bolivia
SPEAKERS
Prof. Dr. Gustavo Zubieta-Calleja, M.D. FPVRI
Head of the High Altitude Pulmonary and Pathology Institute (HAPPI-IPPA)
Chairman
Vice-President of the International Society of Chronic Hypoxia
Ex-Visiting Professor University of Copenhagen
Visiting Professor BLDE University and Era University, India
The Hypoxia Man
Title: "Chronic Hypoxia: a remarkable stimulus for enhanced survival"
Chronic Hypoxia, Poly-erythrocythemia, Tolerance to Hypoxia, Altitude Adaptation formula, Oxygen Transport Triad, Pneumolysis, Low CoVID and other diseases at high altitude, Silent Hypoxemia, Extended Longevity at high altitude, Space travel in a hypoxic environment, Acid-Base high altitude correction factors, Bio-Engineering, High altitude Diving Tables, Chronic Mountain Sickness, Acute Mountain Sickness, Co-Organizer of the First World Congress on High Altitude Medicine and Physiology. Co-organizer of the 8th Chronic Hypoxia Symposiums, builder of the Chacaltaya Glass Pyramid Laboratory, Builder of the Hyperoxic/Hypoxic Adaptation Chambers Versions 1 and 2, Pulmonary function equipment construction, Co-organizer of the Futbol in Sajama at 6542m, Physician with expertise in high altitude medicine.
Prof. Thuppil Venkatesh, M.D.
Foundation for Quality India
President of the International Society of Chronic Hypoxia
Mountaineer and Scientist
The Lead Man of India
Title: "Beneficial effects of “PRANAYAMA” (regulated breathing) at high altitude hypoxic conditions – a new thought"
Title: "The International Society of Chronic Hypoxia: history and the future"
Dr Thuppil Venkatesh is a professor Emeritus at St John’s Medical College Bangalore. He is CEO and the Director of the Foundation for Quality India (FQI) and the Director of the National Referral Centre for Lead Projects in India (NRCLPI). Dr Thuppil is the current National Chairman of the Indian Society for Lead Awareness and Research (InSLAR) (www.inslar.org). He is also called as the Lead Man of India and was director of project Lead Free of The George Foundation which was instrumental in getting the unleaded petrol to India in March 2000. He served as the National Chairman in getting the Gazette notification for defining the limits for lead contents in paints. Dr. Venkatesh is also the Lead/Principal Assessor for the NABL & NABH under Quality Council of India (QCI). He is also the adviser to CAHO and AHPI. Served as an accreditation committee member for NABL, NABH, DAC Dubai and serving as the Chairman of Laboratory Accreditation Board of Nepal. Dr. Venkatesh is President of the International Society of Chronic Hypoxia and visiting professor of Zubieta University, Bolivia and Visiting Scholar of the University of Cincinnati, USA. He is the recipient of the International award for Science, Honor and Truth, prestigious Arya Bhatta Award apart from the life time achievement award from CAHO. He is also technical adviser to UNIDO and WHO. He has published over 350 scientific papers in peer reviewed journals.
Prof. Jan Marino Ramirez, PhD
Director of the Center for Integrative Brain Research
Head Laboratory of Vascular Physiology & Medicine
Seattle Children's Hospital
University of Washington
Seattle, USA
Title: "Unraveling the hypoxic response of the cardiorespiratory network"
Our studies focus on understanding the neuronal basis of a variety of brain functions to find novel ways to treat and cure neurological disorders in children, including epilepsy, Rett syndrome, brain tumors, and sudden infant death syndrome (SIDS). Our current work focuses on the analysis of the in vitro respiratory network in mice. For this purpose we isolate acutely the respiratory network in a transverse plane of the mouse medulla. This brainstem slice preparation contains the essential medullary structures involved in cardio-respiratory control and even after the in vitro isolation generates rhythmic activity in rats and mice of all developmental stages (up to an age of 25 postnatal days). This approach permits a direct comparison of the neuronal mechanisms of rhythmogenesis in newborn and more mature mammals. Our experiments indicate e.g. that the hypoxic response, fast chloride mediated inhibitory synaptic transmission, calcium channels and modulatory processes change postnatally within the respiratory network. He is recipient of the International award for Science, Honor and Truth,
Prof. Michele Samaja, PhD
Professor of Biochemistry
School of Medicine
Universitat di Milano
Milano, Italy
Title: "The response to physiological and pathological hypoxia as a clue to understand hypoxic preconditioning"
Ischemia-Reperfusion Injury High Altitude Blood Heart Ischemia Hypoxia-Inducible Factor 1 Nitric Oxide Physiology Cardiology Acclimatization Cancer Biology Hypoxia Rats
Prof. Vamsi K. Mootha, MD
Howard Hughes Medical Institute
Department of Systems Biology
Harvard Medical School
Department of Medicine
Massachusetts General Hospital
Institute Member
Broad Institute of MIT and Harvard
Boston, Massachusetts, USA
Title: "Hypoxia as a therapy for mitochondrial disorders"
Current Members | Former Members | Principal Investigator shim shim shim shim shim Vamsi K. Mootha, MD Investigator Howard Hughes Medical Institute Professor Department of Systems Biology, Harvard Medical School Department of Medicine, Massachusetts General Hospital Institute Member Broad Institute of MIT and Harvard B.S., Stanford University M.D., Harvard Medical School Joined the Harvard Faculty in 2004 Click here to email Vamsi. shim Vamsi Mootha is an Investigator of the Howard Hughes Medical Institute and a Professor of Systems Biology and of Medicine at Harvard Medical School. His laboratory is based in the Department of Molecular Biology and Center for Genome Medicine at Massachusetts General Hospital. Dr. Mootha leads a research team dedicated to mitochondrial biology. His research team includes biologists, computer scientists, clinicians that work together to investigate mitochondrial bioenergetics in health and in disease. His work has led to the full characterization of the mitochondrial proteome, identification of dozens of disease genes, and discovery of all the components of the mitochondrial calcium uniporter. He and his team have developed computational tools that are now widely used in biomedical research.
Kusal K Das
PhD FRSB(UK)
Professor
Laboratory of Vascular Physiology and Medicine
Department of Physiology
Shri B.M.Patil Medical College
BLDE (Deemed to be University)
Vijayapur-586103, Karnataka, INDIA
Title: "Wnt/β-catenin signalling pathway modulates pulmonary arterial smooth muscle cells (pasmc): role of gallic acid and β-sitosterol"
My Laboratory of Vascular Physiology & Medicine works on understanding of vascular diseases through their complex mechanisms. My works devoted to shape vascular integrity and find out some innovative approaches which may improve the quality of human life or sufferings. I have made some impact contributions on understanding of experimentally induced hypoxia and cell signaling mechanism during heavy metal induced stress and alteration of vascular integrity using an animal as well as human models. My works also extended to cerebral ischemia in experimental models. He is the recipient of the International award for Science, Honor and Truth,
Dr. Richard Wilson PhD
Professor
Cumming School of Medicine
Department of Physiology and Pharmacology
Child Health & Wellness Researcher
Alberta Children's Hospital Research Institute
Hotchkiss Brain Institute
Campus Alberta Neuroscience
University of Calgary
Calgary, alberta, Canada
Title: "Uncapped chemosensitivity: spinal oxygen sensor (sos) activation on the way to the peak "
We are investigating the neuronal control of respiration, focusing primarily on respiratory rhythm generation and chemosensitivity. As many as 20 million people in North America may suffer from sleep apnoea, including 40% of patients with chronic heart failure and 60% of stroke victims. Sudden infant death is the major cause of infant mortality in the first year of life and neonatal apnoea is the primary reason for admission into neonatal intensive care units. The social and economic consequences of these respiratory disorders motivate our investigation into the fundamental mechanisms involved in the neuronal control of respiration.
Dr. Christopher Wilson, PhD.
Professor of Pediatrics and Basic Sciences (Physiology)
School of Medicine
Loma Linda University
Loma Linda, California
Title: "Covid-19 and hypoxia insensitivity: an in silico study"
I have extensive experience with in vivo and in vitro animal models (25+ years). I have written custom analysis software using spreadsheets, Igor Pro, Kaleidagraph, ImageJ, R/S-Plus, and Python. My work is centered on the generation and modulation of respiratory rhythm. Chiefly we use whole-cell patch clamp or extracellular single-unit recording to address the membrane and network properties of neurons involved in generating and transmitting breathing rhythm
Dr. Jay K. Storz, PhD
Willa Cather Professor of Biology
School of Biological Sciences
University of Nebraska
Lincoln, Nebraska, USA
Title: "Andean rodents: evolution and high elevation adaptations"
Disciplines
Virology
Skills and expertise
Small Mammals Systematics Evolution Molecular Phylogenetics Biodiversity Phylogeography and Phylogenetic Biogeography
Christian Arias Reyes , PhD.
Norcliffe Foundation Center for Integrative Brain Research
Seattle Children's Research Institute
Seattle, United Statesa
Title: "Mitochondrial mechanisms of acclimatization to hypoxia in the brain and its therapeutic potential in neurodegenerative diseases"
Metabolic cell and mitochondrial mechanisms of acclimatization to hypoxia. Always in a wider field of the study of life in high altitude.
Disciplines
Physiology Evolutionary Biology Molecular Biology
Skills and expertise
Biomedical Science Cell Culture Gel Electrophoresis Electrophoresis DNA Extraction SDS-PAGEATP Translocases Mitochondrial ADP Plethysmography Reactive Oxygen Species Oxidative Stress High Resolution Respirometry
Dr. Christine Ebert-Santos MD
Ebert Family Clinic
Highaltitudehealth.com
Colorado, USA
Title: "The 'safety factors' protecting against the development of lung edema; a functional interpretation of pulmonary hypertension"
Dr. Chris has grown her experience diagnosing and treating the many different ways the body responds to the high altitude environment. Her research on high altitude pulmonary edema (HAPE) has been published and shared among other high altitude science experts and physicians internationally, and continues to be featured in Colorado media as an expert.
Dr. Trevor Day PhD
Professor of Physiology
Educator, Researcher, Writer, Speaker, Performer
Mount Royal University
University of Calgary
Calgary, Alberta, Canada
Title: "Central sleep apnea with ascent to high altitude: friend or foe?"
His research interests include the integrated physiological responses to acute and chronic blood gas challenges, and he is a leader in organizing high altitude research expeditions. His current scholarly and outreach work includes research in basic and applied human physiology, physiology education and science communication. He also has an active interest in science communication, particularly how scientists can better engage the public in the importance and relevance of the scientific endeavor.
Dr. Sharan Srinivasan M.D.
Neurosurgeon & Director PRS Neurosciences and Mechatronics Research Institute
Bangalore, India
Title: "Functional neurosciences"
Dr. Sharan Srinivasan has performed over 8000 major brain and spine surgeries. He is a member of many national and international professional organizations and has given invited talks & chaired sessions in many regional, national & international conferences. He has been Nominated as the sole Indian national representative in the managing committee of the AOSNR – Asia Oceania Society for NeuroRehabilitation. He was a part of the core organizing committee in charge of WCNR2018 @ Mumbai (World Congress for NeuroRehabilitation)
Dra. Natalia Zubieta-DeUrioste, M.D.
High Altitude Pulmonary and Pathology Institute (HAPPI-IPPA)
La Paz, Bolivia
PHD candidate
University of Calgary,
Calgary, Canada
Title: "Low altitude perypheral edema (lape): the opposite of Hape or Hace"
Chronic Hypoxia, Poly-erythrocythemia, Tolerance to Hypoxia, Altitude Adaptation formula, Oxygen Transport Triad, Pneumolysis, Low CoVID and other diseases at high altitude, Silent Hypoxemia, Extended Longevity at high altitude, Space travel in a hypoxic environment, Chronic Mountain Sickness, Acute Mountain Sickness, Co-organizer of the 6th 7th and 8th Chronic Hypoxia Symposiums, co-Builder of the Hyperoxic/Hypoxic Adaptation Chamber Versions 2, Pulmonary function, Physician with expertise in high altitude medicine.
Dr. Olena Klyuchko, PhD
Associate Professor,
National Aviation University
Kyev, Ukraine
Title: "Effects of radioactive atmospheric components on biological beings at altitudes: development of the information concept"
Starting from brain studies, I continue research work in directions where I can apply in technique my expertize in biophysics, biology, ecology. Doing this,I had discovered some principles, invented devices,techniques, technical systems including "EcoIS"monitoring system (Ecological Information System,see publications). My successes in this were reflected in 31 patents, 385 scientific publications (till Oct2024).
Dr. Zoya Serebrovska, PhD
Head
Department of General and Molecular Pathophysiology
Bogomoletz Institute of Physiology,
Chebotarev State Institute of Gerontology of the NAMS of Ukraine
Kyiv, Ukraine.
Title: "Preimaginal exposure to intermittent hypoxia-hyperoxia cycles mitigate age-related motor decline and alter metabolic and stress-related gene expression in adult drosophila"
Ovarian Hyperstimulation SyndromeReproductionReactive Nitrogen SpeciesReproductive MedicineAzoospermia.
Dr. Roberto Accinelli Tanaka, M.D.
Previous Director Instituto de Investigaciones de la Altura,
University Cayetano Heredia,
Lima, Peru
Title: "Asthma at high altitude"
Pulmonologist, COVID specialist, Anemia at high altitude
Prof. Malali Gowda, PhD
Founder and Head Bangalore Genomics Center
Founder adn Head DNA Life
Bangalore, India
Prof. Walter Calderon Gerstein M.D.
Universidad Continental de Ciencias e Ingenieria
Huancayo, Peru
Title: "Endothelial function at high altitude"
Diabetology Internal Medicine (General Medicine) Cardiology
Skills and expertise
Heart Failure Atrial Fibrillation Cardiac Function Chronic Heart Failure Clinical Cardiology Electrocardiography Blood Pressure Internal Medicine Clinical Physiology
Dr. Jose Antonio Carmona M.D.
Universidad Nacional Autónoma de México
México City, México
Title: "The difference in treatment of traumatic intra-cranial hypertension at sea level and high altitude"
Intensive care Neurocritical care Critical Patient Workshops of neurocritical care
México
Prof. Hamid Mobasheri PhD
UNESCO/UNITWIN
Department of Environmental Health
Network Biophysics Coordinator
Head of Laboratory of Membrane Biophysics and Macromolecules
University of Tehran
Tehran, Iran
Title: "Biophysics of molecular structure and function at low pressures in the lungsn"
His current project is 'The effect of static magnetic fields on neural communication and microtubule organization.' His team tries to understand the biophysical susceptibility of biological systems to magnetic, electric and electromagnetic fields at molecular, cellular and tissue levels. The ultimate aim is to find out the fields' side effect and to apply them as a manipulative means to monitor and tackle cell abnormalities, diseases and pathogenic microorganisms. In summary, he is interested in the physics of cell machinery involving ions, electrons, protons, radicals etc. whose actions are manifested by bioresonance, bioelectronics, bioelectrics, bioimpedance and Bio-nanotech.
Lic. Maximo Liberman
Biologo
Full Professor
Instituto de Ecologia,
Facultad de Ciencias Puras y Naturales
Universidad Mayor de San Andres, La Paz Bolivia
Title: "the routine life of alpaca shepherds at 4,800m in the bolivian andes"
Emeritus Professor Maximo Liberman Cruz, biologist, teacher and researcher of the Ecology Institute at the University of San Andres, in La Paz Bolivia. He studied at the University of Concepción, Chile. Graduated in rural studies at ITC, Enschede, The Nederlands. Visiting Professor at the University, Los Andes, Merida Venezuela, at the Environmental Management Course. Visiting professor of Biogeography and Vegetation of South America course at the University of Camerino, Italy. He has numerous scientific papers and six books published in Bolivia and USA related to: Desertificatión in Bolivia, Land Use Change and Mountain Biodiversity, Land use and Biodiversity Resources in Protected Areas of Bolivia, and Sustainable development of Fragile Ecosystems in the Andean Mountains.
Dr. Hannelore Ehrenreich, MD, DVM
Professor of Neurology and Psychiatry
Prof. Hon. of Biology & Psychology
University of Göttingen
Clinical Neuroscience
Max Planck Institute for Multidisciplinary Sciences
Göttingen, Germany
Title: "Functional hypoxia as a concept explaining health benefits of motor-cognitive training"
Clinical Neuroscience
(1) Genetic and environmental underpinnings of neuropsychiatric diseases;
(2) Endogenous neuroprotection and neuroregeneration as therapeutic strategies for patients: Research centering on the brain erythropoietin system and hypoxia;
(3) Autoimmune and inflammatory processes contributing to neuropsychiatric phenotypes.
Dr. Natalia I. Aranova, PhDDSc (Engineering)
Senior Researcher
Optimization of Controlled Processes,
Glushkov Institute of Cybernetics of National Academy of Sciences of Ukraine,
Kiev, Ukraine
Title: "Intelligent decision support system for selection, training and recovery under extreme loads "
PhD, ScD (Eng). Interests are related to the study of human life in extreme conditions, development and analysis of mathematical models and algorithmic support of the functional human respiratory system in case of disturbances of the external and internal environment, research of reliability, resistance and processes of human adaptation to hypoxic states of various etiologies. Separate directions — transport of respiratory gases through the respiratory and circulatory systems, mental and physical performance of a person during a stay in the highlands, under conditions of increased situational stress. participated in the research and selection of Soviet and Ukrainian climbers who climbed the Himalayan peaks, studied the effect of radiation on the human body, developed methods of treatment and rehabilitation of the irradiated.
Prof. Dr. rer. nat. Elisabeth Deindl
Walter-Brendel-Centre of Experimental Medicine
University Hospital
Biomedical Center Munich
Ludwig-Maximilians-Universität
Munich,Germany
Title: "Impact of extracellular cold-inducible rna-binding protein (ecirp) on inflammation and vascular reorganization"
The development and remodeling of vessels is a crucial process in many physiological and pathophysiological processes making it topic of in-depth research in laboratories all around the world. Vascular occlusive diseases are head of death causing aliments in industrialized countries. Growth of collateral arteries (arteriogenesis) bypassing a site of stenosis is the most relevant naturally occurring adaptive process protecting tissue from ischemic injury and death. The main research interest of the group around E. Deindl is the identification of the molecular pathways of arteriogenesis from increased mechanical load – the trigger of collateral growth - to cell proliferation. In detail, we are studying how physical forces are translated into biological signals, how these signals are propagated within a cell, finally resulting in cell proliferation, as well as how signals are transmitted from cell to cell (i.e. from endothelial cells to smooth muscle cells)
Dr. Andres Alfredo Merino
Residente de 1er año de Cuidados Intensivos
Miembro del Grupo de Investigación de Medicina Intensiva en Altura ( GIMIA)
Bombero Voluntario de la Compañía de Bomberos La Molina 96
Divemaster de Buceo PADI
San Salvador, El Salvador
Title: "Paradoja del lactato en la altura"
Dr. José Manuel Calle
Médico neumólogo
Universidad Tomas Frias
Hospital Daniel Bracamonte
Potosi, Bolivia
Title: "COVID-19 en Potosi a 4000 metros sobre el nivel mar"
Dr. Favio Muñoz
Medico
Centro de Instrucción de Buceo De Altura
Armada Boliviana
Titicaca Lake
Tiquina, Bolivia
Title: "Efectos de la medicina hiperbarica en pacientes con anemia moderada a severa como terapia alternativa de tratamiento a 3810 metros sobre el nivel de mar"
Dr. Gulnura Dzhunusova M.D.
professor
head of the
laboratory of neurophysiology
director of the Institute of mountain
physiology and medicine
of the National academy of sciences of the
Kyrgyz Republic
Title: "Physiological mechanisms of Functional relationships of thyroid hormones and catecholamines in high altitude conditions"
The main direction of research is the study of the neurophysiological
mechanisms of human adaptation under the influence of extreme and mountainous
environmental factors, the assessment of the functional state of a person in order to
predict their activities in extreme and high-mountain environmental conditions, the
identification of disadaptive and functional disorders and their correction by
adaptive biofeedback.
Dr. Thomas Kreck, MD,
Critical Care Medicine
CMO & Co-Founder
Neurosave
San Francisco Bay Area
California, USA
Title: "Fetal hemoglobin is coming. Can it help us in thin air, with bad lungs, and get us to mars?"
NeuroSave develops devices for rapid induction of therapeutic hypothermia. The company is focused on finding treatments for ischemic brain injury due to stroke, cardiac arrest, and surgery. NeuroSave was founded in 2010 and is based in San Francisco, California.