In this 2nd Edition of the Textbook in Medical Physiology And Pathophysiology Essentials and clinical problems, we decided to change the name in order to show that this new version is modified in form and becomes interactive. This digital book uses a new format in order to constantly evolve and improve. Hence the term "New" never becomes outdated, as it is permanently evolving. You are welcome to send us comments or additions in each section where the link comments are posted. Please be brief and try to fit in one sentence an essential concept in physiology. Remember this is a textbook for medical students. And due to the exponential growth of information, they are overwhelmed with data. If you agree your name and/or your affiliation can be included in the comments. This allows for a dynamic physiology book that is often updated with the new exponentially growing information. A new format for future scientific books.

As a comment is posted, we review it and proceed to include it in the book, if appropiate. We have an open mind and this has always been our standing with respect to science. It should be a common good, open to all around the globe. A true globalization of knowledge. That is why the 1st edition published by the first author in 2002 has been so popular. It was the first medical physiology book to be completely free on-line.

Please note that we are not obliged to publish the comments on-line, as we will peer review them first. But you can be sure that we are not biased or just publish your contribution if you are a member of a closed group (as some journals do). Quite the contrary, we are open for any sound, solid scientific contribution from any distinguished colleague (or student) around the world. We base our focus of science on two concepts: "The joy of seeing the light" and "Science, honor and Truth"

Any suggestions as to how to improve this book are most welcome. Enjoy!

Poul-Erik Paulev & Gustavo Zubieta-Calleja